Ongoing existing projects
The NBB has two main types of the biobanking arrangements – disease- or project-specific BioBanks and population based BioBanks
Population Based BioBank
Associated physician:
In the near future, we intend to collect blood and microbiome samples from all of the patients hospitalized in Soroka. Blood samples will be further processed and plasma, serum and white blood cells will be extracted and reserved in the biorepository for further research (including DNA/RNA sequencing in a later phase).
Associated physician:
In the near future, we intend to collect blood and microbiome samples from all of the patients hospitalized in Soroka. Blood samples will be further processed and plasma, serum and white blood cells will be extracted and reserved in the biorepository for further research (including DNA/RNA sequencing in a later phase).
Disease Specific BioBank
Associated physician: Dr. Tehila Kaisman-Elbaz
The Brain Tumor BioBank, is a collection of tumor and blood samples from patients suffering from different types of brain tumors. The purpose of the project is to understand the molecular and genetic mechanisms underlying the formation and progression of different brain tumors and to help development of new diagnostics and therapeutics.
Associated physician: Dr. Joshua Ben-Zion, Dr. Moshe Elkabets
The Head & Neck tumors BioBank will contribute to the development of new diagnostic tools and therapeutic implication on head, neck and thyroid cancer patients. A collection of tumor and blood samples from patients with different types of Head & Neck tumors. Some Tumor samples were used for primary cell-line purification or transplanted into lab mice for further research.
Associated physician: Dr. Yuval Kriger
The purpose of this project is to establish a skin cancers tissue bank, that will allow to understand the molecular and genetic mechanisms leading to the formation of tumors, and help establish new therapeutic strategies and to improve clinical outcomes.
Associated physician: Dr. Tehila Kaisman-Elbaz
The purpose of this project is to understand the molecular and genetic mechanisms resulting in Sub-Dural Hematoma. The main focus of the research will be on verifying the time of occurrence of the traumatic event.
Associated physician: Dr. Itai Levi, Dr. Uri Greenboum
A collection of bone marrow and blood samples from hematology patients. The purpose of this project is to characterize molecular and genetic determinations of hematological tumors and to identify correlates with aggressive phenotypes. In addition, we aim to identify biomarkers for early diagnosis of cancer, therapy and prognostication.
Associated physician: Dr. Alex Geptler
Associated physician:
The purpose of this project is to establish a gynecologic cancers tissue bank. This will allow to understand the molecular and genetic mechanisms leading to the formation of tumors, and help establish new therapeutic strategies and to improve clinical outcomes. The establishment of the proposed BioBank for gynecological cancers will have a significant impact on the development of new diagnostic tools and therapeutic implication on patient treatment.
Israeli Creutzfeldt-Jakob Disease BioBank: A Beacon of Hope in Genetic Research
Introduction:
Welcome to the Israeli Creutzfeldt-Jakob Disease BioBank, a groundbreaking collection of samples dedicated to researching Creutzfeldt-Jakob Disease, a rare neurodegenerative condition.
About Creutzfeldt-Jakob Disease:
Genetic Creutzfeldt-Jakob Disease, while being a global rarity with a prevalence of 1:10 million, sees an unusually high incidence in Israel. Every year, dozens of cases are reported here, with thousands of families believed to carry the genetic mutation causing the disease. Although the disease usually manifests between ages 50-60, there are instances of it appearing as early as 30 and, in recent findings, even in individuals as old as 90. This sheds light on the need to understand what triggers the disease and the role of epigenetic factors.
What's in the BioBank?
In addition to samples from those with the mutation either with or without the disease, we also have a control group comprising relatives without the mutation. Currently, our collection includes blood samples (processed into plasma, serum, peripheral blood mononuclear cells, whole blood), urine, and nasal swabs. We are constantly updating our noninvasive collection methods in response to the evolving needs of researchers.
Our Unique Approach:
This BioBank operates in association with the Creutzfeldt-Jakob Disease Foundation Israel, boasting a registry of hundreds of local families. We've introduced an innovative model of sharing, where we provide samples at minimal costs. In return, we ask researchers to share their findings. This approach promotes collaborative AI-driven research on large datasets, aiming to expedite discoveries related to biomarkers, triggers, early diagnosis, therapeutic targets, and potential treatments.
**Watch Our 2-Minute Animation:**
https://www.youtube.com/watch?v=iG91ddQtb5A
Associated physician: Prof. Gal Ifargan
In the near future, we intend to collect blood and fecal samples from all of the patients hospitalized in the neurological department in Soroka, after experiencing a stroke. The purpose of this project is to allow us to understand the molecular, microbiome and genetic mechanisms leading to the formation of stroke. The establishment of the proposed BioBank will promote clinical studies and help improve patient care quality at Soroka.
Associated physician: Dr. Naim Abu Friha